Hydrocephalus
Hydrocephalus is the excessive accumulation of cerebrospinal fluid (CSF) within the cavities of the brain (ventricles). This buildup can raise intracranial pressure and compress brain tissue, producing a range of neurological symptoms.
마지막 업데이트: 2026-06-06
Definition
Hydrocephalus is fluid accumulation and ventricular enlargement resulting from an imbalance in CSF production, circulation or absorption. Obstruction of CSF flow produces obstructive (non-communicating) hydrocephalus, whereas impaired absorption causes communicating hydrocephalus. Normal pressure hydrocephalus is a distinct subtype in adults.
Causes and Risk Factors
Congenital causes include aqueductal stenosis and neural tube defects. Acquired causes include brain hemorrhage (especially subarachnoid hemorrhage), infections such as meningitis, brain tumors and head trauma. Normal pressure hydrocephalus is most often seen in older adults.
Symptoms
In infants, rapid head growth, a tense fontanelle and irritability are seen. In children and adults, headache, nausea and vomiting, visual disturbance, balance problems and altered consciousness may occur. The classic triad of normal pressure hydrocephalus is gait disturbance, urinary incontinence and cognitive decline.
Diagnosis
Diagnosis relies on imaging; computed tomography (CT) and magnetic resonance imaging (MRI) show ventricular enlargement and the likely cause. Cranial ultrasound through the fontanelle can be used in infants. In normal pressure hydrocephalus, a CSF tap test (high-volume lumbar puncture) may help predict response to treatment.
Treatment
Treatment aims to reduce CSF accumulation. The most common method is a ventriculoperitoneal (VP) shunt, which diverts excess fluid to another cavity (usually the abdomen). In selected obstructive cases, endoscopic third ventriculostomy (ETV) can be an alternative to shunting. The choice depends on the type and cause of hydrocephalus.
Prognosis
With early diagnosis and appropriate treatment, symptoms can be controlled in many patients; however, complications such as shunt malfunction and infection require follow-up. Prognosis depends on the underlying cause, the patient's age and response to treatment; outcomes vary individually.
참고 문헌
- Greenberg MS. Greenberg's Handbook of Neurosurgery. 10th ed. Thieme; 2023:426-479.
- Winn HR, ed. Youmans Neurological Surgery. 6th ed. Saunders; 2011:495-514.
- Rekate HL. A consensus on the classification of hydrocephalus: its utility in the assessment of abnormalities of cerebrospinal fluid dynamics. Childs Nerv Syst. 2011;27(10):1535-1541.
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